Spectraplakins: The Cytoskeleton's Swiss Army Knife

Multipurpose Identity-Based Sign ryption A Swiss Army Knife for Identity-Based Cryptography

Dimethyltryptamine (DMT): a biochemical Swiss Army knife in neuroinflammation and neuroprotection?

Dissecting the Pathophysiology of Depression with a Swiss Army Knife

In this issue of Neuron, Hen and colleagues shed new light on the behavioral effects of fluoxetine, one of the most commonly prescribed antidepressants. This report prompts us to revisit our understanding of the neural circuitry mediating mood disorders and also provides a framework for developing new antidepressant treatments.

The plasmacytoid dendritic cell as the Swiss army knife of the immune system: molecular regulation of its multifaceted functions.

Plasmacytoid dendritic cells (pDC) have been regarded as the "professional type I IFN-producing cells" of the immune system following viral recognition that relies on the expression of TLR7 and TLR9. Furthermore, pDC link the innate and adaptive immune systems via cytokine production and Ag presentation. More recently, their ability to induce tolerance and cytotoxicity has been added to their "...

GAL4 system in Drosophila: a fly geneticist's Swiss army knife.

The last decade has seen an enormous expansion in the genetic toolbox of model organisms. This has been particularly apparent in the fruitfly, Drosophila melanogaster, in which the development of these tools and their ongoing extension, along with the completion of the genome sequence has allowed for the analysis of most any process. One particularly elegant example of tool development was the ...